Today : Tuesday - Sep 02, 2014, 05:10pm (GMT+5.5)
All News  
Top News
National News
International News
Business News
Sports News
   » Cricket
   » Football
Entertainment News
Sci - Tech
Politics News
Health & Fitness
Education
Travel
Lifestyle
Gulf News
Featured
 
::| Latest News
News in Pictures

Nelson Mandela, who is although seriously sick, is the one making decisions about his own fate, his daughter has said.The comments were made by Zindzi in a joint interview with mother, Winnie Madikizela-Mandela, with British television ITN.They both were critical of public discussions about whether or not the family should keep the ailing Nobel peace laureate alive, news.com.au reports.

Health & Fitness
 

Faulty genes precipitate bowel cancer risk

Tuesday - Dec 25, 2012, 11:22am (GMT+5.5)
[+] Text [-]

London - Faulty genes precipitate bowel cancer risk in families which have a history of this condition, according to a British study.

Researchers from Oxford University and The Institute of Cancer Research, London, found everyone who had a faulty gene 'POLE' or 'POLD1' developed bowel cancer or had a precancerous growth in the bowel.

The researchers then further looked at 4,000 people with bowel cancer and 6,700 healthy people, the journal Nature Genetics reports.

Neither of the faults were found in people without bowel cancer, while 12 people with the POLE gene were found in the bowel cancer group and a person had a POLD1 gene fault, according to the Telegraph.

POLE and POLD1 are involved in scanning and repairing damage to DNA, removing incorrect sequences from the DNA chain. Without them, affected individuals build up damage in their DNA which can cause bowel cancer.

The POLD1 fault was also found to increase the risk of getting womb cancer and possibly brain tumours with seven people in the study being diagnosed with womb cancer and one developing two brain tumours.

Richard Houlston, professor from The Institute of Cancer Research said: "Uncovering gene faults like these two is extremely important, as inherited susceptibility plays a role in the development of about a third of all the cases of Colorectal Cancer."

"This is one of the most important discoveries in bowel cancer genetics in years. It should allow us to manage families affected by inherited bowel cancer much more effectively, and it offers new clues for the prevention or treatment of all forms of the disease," Houlston concluded.





|

Rating (Votes: )   

blog comments powered by Disqus

Other Articles:
Being alone as hazardous to health as smoking 15 cigarettes every day (25th Dec, 2012)
Why chocolate milk is the best post-workout drink (24th Dec, 2012)
Scientists map how brain makes sense of what we see (24th Dec, 2012)
Flying champagne corks can cause serious, blinding eye injuries (24th Dec, 2012)
Researchers uncover genetic cause of eczema (24th Dec, 2012)
Cuban scientists seek cancer cure from scorpion venom (24th Dec, 2012)
Top Cardiac Surgeon Dr Hariawala unveils ``Triple Heart Therapy`` at CSI 2012 (24th Dec, 2012)
Indonesia culls over 100,000 ducks to stop bird flu (24th Dec, 2012)
Six die after virus outbreak at Japanese hospital (24th Dec, 2012)
Music has healing power (24th Dec, 2012)
Flying champagne corks can cause serious, blinding eye injuries (24th Dec, 2012)
Chicken soup can really help fight cold (23rd Dec, 2012)
New nerve cell regulating heart rhythm identified (23rd Dec, 2012)
Too much `sugary and fatty` food can weaken your bones (23rd Dec, 2012)
How to avoid weight gain during this party season (23rd Dec, 2012)
For that winter skin glow: keep it hydrated, moisturised (23rd Dec, 2012)
Test to detect pre-menstrual syndrome in the pipeline (22nd Dec, 2012)
Men benefit most from eating dark chocolate (22nd Dec, 2012)
X-ray lasers help fight sleeping sickness (22nd Dec, 2012)
PMS mood swings `may just be a myth` (22nd Dec, 2012)
Gut taste buds targeted to fight obesity (22nd Dec, 2012)
Detox diets could be harmful for liver disease patients (21st Dec, 2012)
A 1 in 3 men wax their crotches as part of their grooming routine (21st Dec, 2012)
Robotic surgery in Tripura hospital soon (21st Dec, 2012)
Half the benefit of sleeping pills comes from `placebo effect` (21st Dec, 2012)




Contact Us | Advertise with Us | Privacy Policy | Disclaimer | Terms of Use